Improving Subject Compliance with Smart Pill Bottles

Improving Subject Compliance with Smart Pill Bottles
According to the American Heart Association, 12% of patients never fill their prescriptions, 12% fill them but do not take them, and 29% start taking them but stop prematurely. Only 47% take them all (1).

  • Improve Outcomes: e-pill reminders increase adherence from the current level of 50% up to 90%+
  • Reduces Cost: Adherent patients are healthier and less expensive to care for. Pill vial / pill bottle reminders are an inexpensive alternative.
  • Easy to Use: Minimal set up for patients, and the smart e-pill bottle works for liquids and oral solids (pills of all sizes).
  • Clinical Studies: Compliance by subjects in clinical trials can be much improved with even the simplest of e-pill Medication Reminders.


  • Proven TimeCap | Compliance Statistics | e-pills used in Clinical Studies


    Learn more: Improving Subject Compliance with Smart Pill Bottles Norman Goldfab First Clinical

    References 1. “Statistics you need to know”, American Heart Association, last accessed 7/18/2005 at https://www.americanheart.org/presenter.jhtml?identifier=107. 2. “Adherence to Medication”, Lars Osterberg and Terence Blaschke, New England Journal of Medicine, August 4, 2005 3. “Medication Compliance as a Feature in Drug Development”, H. Kastrissios and T.F. Blaschke, Annual Review Pharmacology & Toxicology, 1997 4. “Addressing Expanded Clinical Trials”, David Vaczek, Pharmaceutical & Medical Packaging News, April 2007

    e-pill Multi-Alarm PLUS Pill Timer Pillbox e-pill Multi-Alarm PLUS Pill Timer Pillbox is a 7-compartment pillbox that uses manual switches to set alarm times. e-pill offers a broad range of “medication reminders,” including the CADEX Medication Reminder Watch, which can be used with regular drug packaging such as blister packs.
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